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Thursday, 30 January 2014

Mitochondrial DNA sequence research in birds; helping to understand evolution and speciation.

Mitochondria are the power-stations of the cell, producing an energy supply for the various cellular processes. To ensure this demand never fails, these organelles have their own DNA that is separate from the majority of the cell's DNA that is kept in the nucleus. This mtDNA has a relatively short sequence and codes for only a few genes. The 16,775 base-pair mitochondrial genome of the white Leghorn chicken has been cloned and sequenced, and has a set of 37 genes for 13 proteins, 2 ribosomal RNAs and 22 transfer RNAs. Mitochondrial DNA sequencing can be used as a type of 'genetic barcoding' that allows for examination of evolution and species definition. An example of such work can be seen in the following paper on Black-Tailed Godwits.

Patterns in Nuclear and Mitochondrial DNA Reveal Historical and Recent Isolation in the Black-Tailed Godwit (Limosa limosa)


Krijn B. Trimbos, Camiel Doorenweerd, Ken Kraaijeveld, C. J. M. Musters, Niko M. Groen, Peter de Knijff, Theunis Piersma, and Geert R. de Snoo
PLoS One. 2014; 9(1): e83949.
Published online 2014 January 9.
LINK

As can be seen in the selection of recent articles below from only one journal 'Mitochondrial DNA' there is a significant amount of work being undertaken in this field with respect to avian genetics studies.

Complete mitochondrial genome of Yellow-browed warbler Phylloscopus inornatus inornatus (Passeriformes: Sylviidae)
Posted online on January 10, 2014. 

Hui Qing, et al

Abstract
Yellow-browed warbler Phylloscopus inornatus inornatus (Passeriformes: Sylviidae) is a small insectivorous leaf-gleaning bird which breeds in forests of the east Palaearctic. In this study, we used PCR-based method to determine the complete mitochondrial genome (mtDNA) of this warbler species. The complete mtDNA is a 16,875 bp circular molecule, containing 37 typical genes and an extra pseudo-control region. The gene order differs from the standard gene order in birds, but similar to genus Sylvia and Acrocephalus, which has the remnant CR2 gene order. All protein-coding genes start with a typical ATG codon. The termination codon is usually the standard TAA, but may be TAG (Cyt b and ND6), AGG (COI) or incomplete T-(COIII and ND4). All tRNAs have the typical clover-leaf structure, except the dihydrouridine (DHU) arm of tRNASer (AGN) and tRNALys (CUN), which forms a simple loop. The non-coding region contains some intergenic spacers, a control region and an extra pseudo-control region.

Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.863299

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Complete mitochondrial genome of Germain’s Peacock-Pheasant Polyplectron germaini (Aves, Galliformes, Phasianidae)
Posted online on January 27, 2014. 

Destiny Omeire, et al

Abstract
The Germain’s Peacock-Pheasant Polyplectron germaini (Aves, Galliformes, Phasianidae) is classified as Near Threatened on the IUCN Red List. The complete mitochondrial genome of P. germaini is 16,699 bp, consisting of 13 protein-coding genes, 2 rRNA, 22 tRNA genes and 1 control region. All of the 13 protein-coding genes have ATG as start codon. Eight of the 13 protein-coding genes have TAA as stop codon.

Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.830292

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An effective strategy for species identification of avian meats using the mitochondrial 12S rRNA gene fragment
Posted online on January 27, 2014. 

Lan-Ping Wang, et al

Abstract
An effective DNA-based molecular method had been used to identify avian species from meats. The method combined the use of a pair of universal primers, which amplified about 440-bp fragment of the mitochondrial 12S rRNA gene. A total of 99 meat samples were tested and 17 haplotypes were identified by DNA sequencing, which representing 14 avian species. One avian species was listed as the national first-grade protected animal in China and the IUCN endangered species. Two avian species were under the national second-grade state protection. The proposed method represents a straightforward and robust method for the accurate identification of avian species that could be used by law enforcement agencies as a tool for the control of illegal trade of meat from protected species.


Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.845769

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Complete mitochondrial genome of black grouse (Lyrurus tetrix)
Posted online on January 22, 2014. 

Bo Li1, et al

Abstract
We sequenced the entire mitochondrial genome of Lyrurus tetrix for the first time. The mitogenome was 16,677 bp in length, encoded with a standard set of 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes plus a putative control region. Almost all genes were encoded on the H-strand except the ND6 and eight tRNA genes. All protein-coding genes initiated with ATG, except for COX1 and ND5 (GTG). An 18-bp-nucleotide deletion occured in the ND6 of Lyrurus tetrix in contrast to other Galliformes. The total base composition of the mitogenome was 30.4% for A, 30.4% for C, 25.8% for T and 13.4% for G. These results provide basic information for phylogenetic analyses among Galliformes.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.878911

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The complete mitochondrial genome sequence of the Daweishan Mini chicken
Posted online on January 22, 2014. 

Ming-Li Yan, et al

Abstract
Daweishan Mini chicken is a valuable chicken breed in China. In this study, the complete mitochondrial genome sequence of Daweishan Mini chicken using PCR amplification, sequencing and assembling has been obtained for the first time. The total length of the mitochondrial genome was 16,785 bp, with the base composition of 30.26% A, 23.73% T, 32.51% C, 13.51% G. It contained 37 genes (2 ribosomal RNA genes, 13 protein-coding genes, 22 transfer RNA genes) and a major non-coding control region (D-loop region). The protein start codons are ATG, except for COX1 that begins with GTG. The complete mitochondrial genome sequence of Daweishan Mini chicken provides an important data set for further investigation on the phylogenetic relationships within Gallus gallus.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.878913

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The complete mitochondrial genome of Garrulax cineraceus (Aves, Passeriformes, Timaliidae)
Posted online on January 22, 2014. 

Hui Xue, et al

Abstract
The complete sequence of the mitochondrial DNA genome from Garrulax cineraceus was determined using the polymerase chain reaction method. The genome (17,800 bp in length) contained 37 genes (13 protein-coding genes, 2 rRNA genes and 22 tRNA genes) and 2 control regions (D-loop) at two different locations of mitogenome, which is similar to the typical mtDNA of vertebrates. All the protein-coding genes in G. cineraceus were distributed on the H-strand, except for the ND6 subunit gene and eight tRNA genes which were encoded on the L-strand.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.878917

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Mitochondrial genome of the Anas crecca (Anatidae: Anas)
Posted online on January 17, 2014. 

Chaochao Hu, et al

Abstract
Mitochondrial DNA plays an important role in living organisms, and has been used as a powerful molecular marker in various evolutionary studies. In this study, we determined the complete mitochondrial genome of Anas crecca (16,601 bp in length). Similar to the typical mtDNA of vertebrates, it contained 37 genes (13 protein-coding genes, 2 rRNA genes and 22 tRNA genes) and a non-coding region (D-loop). Overall base composition of the complete mitochondrial DNA was 29.05% A, 22.35% T, 32.64% C and 15.96% G.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.834434

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The complete mitochondrial genome of the Xuefeng black-boned chicken
Posted online on January 17, 2014. 

Li-Li Liu, et al

Abstract
Xuefeng black-boned chicken is one of the famous native breeds in China. In this work, we reported the complete mitochondrial genome sequence of the Xuefeng black-boned chicken for the first time, which was determined through PCR-based method. The total length of the mitogenome was 16,783 bp, with the base composition of 30.24% for A, 23.72% for T, 32.52% for C, 13.53% for G, in the order C > A > T > G feature occurring in the Xuefeng black-boned chicken. It contained the typical structure, including 2 ribosomal RNA genes, 13 protein-coding genes, 22 transfer RNA genes and 1 non-coding control region (D-loop region). It was similar to the gene arrangement in Silky chicken. The complete mitochondrial genome sequence of the Xuefeng black-boned chicken provided an important data for further study on the genetic mechanism.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.869679

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The complete mitochondrial genome of the Feral Rock Pigeon (Columba livia breed feral)
Posted online on January 17, 2014. 

Chun-Hong Li, et al

Abstract
In the present work, we report the complete mitochondrial genome sequence of feral rock pigeon for the first time. The total length of the mitogenome was 17,239 bp with the base composition of 30.3% for A, 24.0% for T, 31.9% for C, and 13.8% for G and an A–T (54.3 %)-rich feature was detected. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region (D-loop region). The arrangement of all genes was identical to the typical mitochondrial genomes of pigeon. The complete mitochondrial genome sequence of feral rock pigeon would serve as an important data set of the germplasm resources for further study.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.873914

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Complete mitochondrial genome of Tundra swan Cygnus columbianus jankowskii (Anseriformes: Anatidae)
Posted online on January 17, 2014. 

Jinghua Wang, et al

Abstract
Cygnus columbianus jankowskii is a subspecies of Tundra swan, which breeds in eastern Russia and northeast China, wintering in the middle and lower reaches of the Yangtze River. In this study, we used PCR-based method to obtain the complete mtDNA of this subspecies. The arrangement pattern of the complete mtDNA is identical with typical bird species, which is the shortest (16,723 bp) in three subspecies. The length of the PCGs is same except ND2, ND3 and ND6, and the initiation/termination codons are all same with other subspecies. The length of 12S rRNA and 16S rRNA is same with C. c. columbianus, but different from C. c. bewickii. The length and structure of all tRNAs are the same with other subspecies except for tRNAIle, tRNAleu(CUN) and tRNAser(AGY). The control region is located between tRNAPhe and tRNAGlu, but the length is different with others.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.873917

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Mitochondrial genome sequence of Egyptian swift Rock Pigeon (Columba livia breed Egyptian swift)
Posted online on January 17, 2014. 

Chun-Hong Li, et al

Abstract
The Egyptian swift Rock Pigeon is a breed of fancy pigeon developed over many years of selective breeding. In this work, we report the complete mitochondrial genome sequence of Egyptian swift Rock Pigeon. The total length of the mitogenome was 17,239 bp and its overall base composition was estimated to be 30.2% for A, 24.0% for T, 31.9% for C and 13.9% for G, indicating an A–T (54.2%)-rich feature in the mitogenome. It contained the typical structure of 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and a non-coding control region (D-loop region). The complete mitochondrial genome sequence of Egyptian swift Rock Pigeon would serve as an important data set of the germplasm resources for further study.



Read More: http://informahealthcare.com/doi/abs/10.3109/19401736.2013.873931

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Monday, 27 January 2014

Current BBSRC research grants including the words 'bird' or 'avian' as of 27th January 2014

Biotechnology and Biological Sciences Research Council, UK.
List of current grants including 'bird' or 'avian' as of 27th January 2014.
This is a long list (113 entries) - please search for topics, Principal Investigators, or Institutes of interest.
BBSRC

BB/E024459/2 
Glucocorticoids and phenotypic programming in birds.
Dr Karen Spencer, University of St Andrews 
£257,503

BB/H018603/1 
Do Cationic Antimicrobial Peptides(CAMPs) impact on the microbiota & consequent gut health of commercially important broilers?
Dr Judith Hall, Newcastle University 
£317,652

BBS/E/I/00001650 
Characterising chicken susceptibility/ resistance markers for avian Influenza virus.
Professor Venugopal Nair, The Pirbright Institute 
£399,910

BB/E009611/1 
Viral & host immunomodulators in improved Fowlpox virus recombinant vector vaccines for use in poultry against highly pathogenic Avian Influenza H5N1.
Dr Colin Butter, The Pirbright Institute 
£581,559

BBS/E/I/00001308 
Viral and host immunomodulators in improved fowlpox virus recombinant vector vaccine for use in poultry against highly pathogenic avian influenza H5N1.
Dr Colin Butter, The Pirbright Institute 
£20,261

BBS/E/I/00001463 
Development of rationally attenuated live vaccines for
effective control of infectious bronchitis.
Professor Paul Britton, The Pirbright Institute 
£406,715

BB/H009027/1 
Development of an improved(DIVA) vaccine against peste des
petits ruminants and technology for a control strategy in endemic
areas.
Dr Michael Baron, The Pirbright Institute 
£787,014

BB/E009956/1 
Viral & host immunomodulators in improved Fowlpox virus
recombinant vector vaccines for use in poultry against highly
pathogenic Avian Influenza H5N1.
Dr Michael Skinner, Imperial College London 
£376,295

BBS/E/I/00001309 
Virus transmission dynamics and the immune response of birds to
avian influenza.
Dr Colin Butter, The Pirbright Institute 
£417,381

BB/H01425X/1 
Development of rationally attenuated live vaccines for
effective control of infectious bronchitis.
Professor Paul Britton, The Pirbright Institute 
£810,482

BB/H016171/1 
Biomarkers of the innate immune response to disease in chickens:
acute phase proteins and resistance to disease.
Professor Peter Eckersall, University of Glasgow 
£75,281

BB/H009337/2 
Anticoccidial vaccine development: the importance of genetic diversity and delivery strategy.
Professor Fiona Tomley, Royal Veterinary College 
£867,142

BB/H019979/1 
Investigating microRNA:target gene interactions in myogenesis.
Professor Andrea Munsterberg, University of East Anglia 
£509,699

BB/E011691/1 
Virus transmission dynamics and the immune response of birds to
avian influenza.
Dr Colin Butter, The Pirbright Institute 
£1,534,407

BB/H022716/1 
Avoiding the costs of testosterone: testing a novel pathway for the regulation of aggression.
Dr Andrew Young, University of Exeter 
£913,396

BB/H531427/1 
The Immunology of Poultry Vaccination.
Dr Colin Butter, The Pirbright Institute 
£25,581

BB/H021817/2 
The evolution of corvid intelligence: development mechanisms and function of cognitive abilities in wild jackdaws.
Dr Alex Thornton, University of Exeter 
£518,506

BBS/E/D/20320000 
National Capability Grant - National Avian Research Facility.
Professor Peter Kaiser, University of Edinburgh 
£224,958

BB/G023913/2 
The ecological cultural and cognitive context of tool use in
New Caledonian crows.
Dr Christian Rutz, University of St Andrews 
£563,653

BB/I011323/1 
A novel role for the chemokine lymphotactin and its receptor in
trigeminal sensitisation.
Professor F Boissonade, University of Sheffield 
£368,888

BB/H017178/1 
Molecular convergence at thesequence level: a genome-wide approach in a novel mammalian model.
Dr Stephen Rossiter, Queen Mary, University of London
£346,204

BBS/E/I/00001774 
PIR Fellowship: in Avian immune responses and signalling.
Professor VenugopalNair, The Pirbright Institute 
£189,879

BBS/E/I/00001707 
To investigate the role of autophagy in the replication cycles
of avian viruses. 
Professor Paul Britton, The Pirbright Institute 
£211,172

BB/I024674/1 
Production systems bird welfare and endemic disease affect the
susceptibility of chickens to Campylobacter.
Professor Tom Humphrey, University of Liverpool 
£458,538

BB/I001182/1 
Novel aptamer-based diagnostics and antiviral therapeutics for
animal influenza viruses. 
Dr Munir Iqbal, The Pirbright Institute 
£446,109

BB/I017577/1 
Marek's disease virus spread: In and out of chickens.
Professor Venugopal Nair, The Pirbright Institute 
£348,459

BB/I000690/1 
The incentive value of a natural and cognitively demanding
behaviour: food-caching jays as a model system.
Professor Nicola Clayton, University of Cambridge 
£404,041

BB/I011668/1 
The morpho-functional evolution of bird beaks and skulls.
Dr Emily Rayfield,  University of Bristol 
£327,929

BB/I011714/1 
The morpho-functional evolution of bird beaks and skulls.
Dr Samuel Cobb, University of Hull 
£39,652

BB/I000615/1 
Modelling systems for managing bee disease: the epidemiology of
European Foul Brood.
Professor Matthew Keeling, University of Warwick 
£165,362

BB/I01361X/1 
Defining the cistrome and quantitative transcriptome of virus
-transformed cells using massively parallel sequencing.
Mr Michael Watson, University of Edinburgh 
£342,819

BB/H020195/2 
Recombinant vaccines for poultry: the use of attenuated Eimeria acervulina as a novel live delivery vehicle for viral vaccines. 
Professor Fiona Tomley, Royal Veterinary College 
£508,311

BB/I001824/1 
Novel aptamer-based diagnostics and antiviral therapeutics for
animal influenza viruses.
Professor Anthony Cass, Imperial College London 
£375,606

BB/I024313/1 
Advanced Training in Intensive Livestock Health and Production.
Professor Stephen May, Royal Veterinary College 
£2,907,160

BB/I019634/1 
The Cognition of Nest Building.
Dr Simone Meddle, University of Edinburgh 
£60,964

BB/I019502/1 
The cognition of nest building.
Dr Susan Healy, University of St Andrews 
£514,051

BB/J015474/1 
Production of genetically modified chickens resistant to major avian respiratory viral pathogens.
Professor Helen Sang, University of Edinburgh 
£345,773

BB/J017108/1 
Production of genetically modified chickens resistant to important avian respiratory diseases.
Dr Laurence Tiley, University of Cambridge 
£535,742

BBS/E/I/00001711 
Genetic analysis of arbovirus transmission by insect vectors. 
Dr Mark Fife, The Pirbright Institute 
£192,657

BB/J020257/1 
China-Vietnam-United Kingdom Partnership in combating viral
diseases of poultry.
Professor Venugopal Nair, The Pirbright Institute 
£24,293

BBS/E/I/00001706 
Use of reverse genetics systems to study avian viruses responsible for endemic diseases and the development of novel vaccine strategies.
Professor Paul Britton, The Pirbright Institute 
£173,944

BBS/E/I/00001721 
Investigate the role of avian viral diseases in the modification of host epigenetic factors and translational control.
Professor Venugopal Nair, The Pirbright Institute 
£541,379

BBS/E/I/00001712 
Molecular and genetic determinants of virus-host interactions affecting pathogenicity.
Dr Mark Fife, The Pirbright Institute 
£359,202

BBS/E/D/20241866 
Novel strategies to control virus infection and disease.
Professor Paul Digard, University of Edinburgh 
£641,686

BBS/E/I/00001704 Molecular interactions in oncogenesis by avian oncogenic viruses.
Professor Venugopal Nair, The Pirbright Institute 
£1,028,081

BBS/E/I/00001708 
Determinants of transmission,adaptation and pathogenicity of
avian influenza.
Dr Munir Iqbal, The Pirbright Institute 
£822,495

BBS/E/I/00001480 
Correlation of immunogenicity with microarray analysis of vector
mutants to improve live recombinant poxvirus vaccines in poultry.
Dr Colin Butter, The Pirbright Institute 
£17,324

BBS/E/I/00001705 
Generation of molecules, tools and reagents for pathogen recognition, antigen presentation and effector responses in avians. 
Dr Colin Butter, The Pirbright Institute 
£655,660

BBS/E/D/20231760 
The impact of host genetic variation on susceptibility and pathology. 
Professor David Gally, University of Edinburgh 
£920,620

BB/H007016/1 
Correlation of immunogenicity with microarray analysis of vector
mutants to improve live recombinant poxvirus vaccines in poultry.
Dr Colin Butter, The Pirbright Institute 
£569,923

BBS/E/I/00001758 
IAH:studentship:The role of AKT activation during Avian Infectious Bronchitis Virus infections.
Dr Mark Fife, The Pirbright Institute 
£28,644

BBS/E/I/00001759 
Identification of genetic markers in the haemagglutinin glycoprotein critical for antigeni activity of H9N2 avian influenza viruses.
Dr Munir Iqbal, The Pirbright Institute 
£32,620

BB/J016446/1 
Early-life adversity and adult cognition: the starling as an
experimental model.
Professor Melissa Bateson, Newcastle University 
£357,650

BB/J017124/1 
Parameterisation of developmental networks to understand periodic patterning.
Dr Kevin Painter, Heriot-Watt University 
£45,510

BB/J014109/1 
Species interactions and the evolution of biological diversity:
visual signalling in antagonistic and mutalistic coevolution.
Dr Claire Spottiswoode, University of Cambridge 
£911,470

BB/J015067/1 
The assembly and function of the TREX complex.
Professor S Wilson, University of Sheffield 
£426,391

BB/J015091/1 
Early life adversity, telomere length and adult cognition: the
starling as an experimental model.
Professor Pat Monaghan, University of Glasgow 
£92,858

BB/J016292/1 
Early life adversity and adult cognition: the starling as an
experimental model.
Dr Karen Spencer, University of St Andrews 
£26,276

BB/G022887/2 
Predator vision and defensive coloration: from mechanism to
function.
Dr Martin Stevens, University of Exeter 
£295,640

BB/K004468/1 
Development of immune function and avian gut health.
Dr Adrian Smith, University of Oxford 
£281,639

BB/I014284/1 
Defining the cistrome and quantitative transcriptome of virus
-transformed cells using massively parallel sequencing.
Professor Venugopal Nair, The Pirbright Institute 
£442,579

BB/J000272/1 
Counter shaded animal patterns: from photons to form.
Professor Julie Harris. University of St Andrews 
£314,325

BB/J000337/1 
Counter shaded animal patterns: from photons to form.
Professor Graeme Ruxton, University of St Andrews 
£10,535

BB/J006815/1 
Mapping resistance to Campylobacter in the chicken.
Professor Peter Kaiser, University of Edinburgh 
£462,693

BB/J016837/1 
Role of AKT1 & SIVA1 in resistance to avian salmonellosis.
Dr Mark Fife, The Pirbright Institute 
£108,941

BB/K000055/1 
CamChain - Campylobacter in chicken production: survival,
virulence and control.
Dr Nicola Williams, University of Liverpool 
£563,078

BB/J018791/1 
Genetic basis of reproductive and plumage polymorphism in the ruff.
Professor Mark Blaxter, University of Edinburgh 
£141,026

BB/I024542/1 
Campylobacter phase variation and its impact on immunity and
vaccine development.
Dr Michael Jones, University of Nottingham 
£292,546

BB/I024712/1 
Campylobacter phase variation and its impact on immunity and
vaccine development.
Dr Christopher Bayliss, University of Leicester 
£92,742

BB/J002372/1 
Counter shaded animal patterns: from photons to form.
Professor Innes Cuthill, University of Bristol 
£79,521

BB/J017353/1 
Susceptibility of broiler chickens to Campylobacter: impacts of the gut environment and immune status on colonisation.
Professor Tom Humphrey, University of Liverpool 
£479,785

BB/K004492/1 
Epi-SEQ - Molecular epidemiology of epizootic diseases using next
generation sequencing technology. 
Dr Donald King, The Pirbright Institute 
£432,404

BB/K004514/1 
CamChain - Campylobacter in chicken production: survival, virulence and control.
Professor Duncan Maskell, University of Cambridge 
£533,121

BB/K002465/1 
Developing Rapid Responses to Emerging Virus Infections of
Poultry (DRREVIP).
Dr Michael Skinner, Imperial College London 
£5,069,406

BB/K005510/1 
A novel bacterial defence system against antimicrobial peptides:
Implications for host colonisation in the food-borne pathogen Campylobacter jejuni.
Professor David Kelly, University of Sheffield 
£349,792

BB/K001906/1 
A Mathematical Modelling approach to defining factors which cause keel fractures in free range laying hens.
Dr John Tarlton, University of Bristol 
£531,992

BB/H002006/2 
Expression of the chicken W chromosome and the evolution of female phenotypes.
Professor Judith Mank, University College London 
£38,949

BB/K011057/1 
Vaccines as drivers of disease emergence: transmission ecology
and virulence evolution in Marek's disease.
Professor Venugopal Nair, The Pirbright Institute 
£992,013

BBS/E/I/00001760
Is PB1-F2 a virulence factor for avian influenza virus in poultry?
Dr Holly Shelton, The Pirbright Institute 
£16,461

BB/J015296/1 
Role of AKT1 & SIVA1 in resistance to avian salmonellosis.
Professor Mark Stevens, University of Edinburgh 
£371,438

BB/J018309/2 
Predator Vision and Avian Egg Camouflage.
Dr Martin Stevens, University of Exeter 
£334,022

BB/L00397X/1 
Restriction of avian viruses by host interferon-inducible
transmembrane proteins (IFITMs).
Professor Paul Kellam, The Wellcome Trust
Sanger Institute
£266,363 

BB/K008226/2 
Genome assembly. chromosomal organization and comparative
genomics of multiple bird species: beyond "catalogues of genes".
Dr Denis Larkin, Royal Veterinary College 
£268,643

BB/K008161/1 
Genome assembly. chromosomal organization and comparative genomics of multiple bird species: beyond "catalogues of genes".
Professor Darren Griffin, University of Kent 
£535,556

BB/K021362/1 
India-United Kingdom Bioinformatics Network.
Dr Jan Kim, The Pirbright Institute 
£25,510

BB/L004240/1 
Enhancing potency and efficacy of herpesvirus of turkeys-based
multivalent vaccines against avian influenza viruses.
Dr Munir Iqbal, The Pirbright Institute 
£126,746

BB/L003996/1 
Restriction of avian viruses by host interferon-inducible transmembrane proteins (IFITMs).
Dr Mark Fife, The Pirbright Institute 
£345,713

BB/L003988/1 
Selection Versus Mutation: Reducing the Risk of Vaccine
Reversion.
Professor Paul Britton, The Pirbright Institute 
£338,811

BB/K002775/1 
Thermography as a tool for the assessment of stress and affective
states in an avian model.
Dr Dorothy McKeegan, University of Glasgow 
£364,775

BB/K021206/1 
International workshop on "Recent Advances in Viral diseases of animals-implications on One Health".
Professor Venugopal Nair, The Pirbright Institute 
£9,879

BB/L000199/1 
Investigating how the type and quantity of food affect foraging behaviour and the neural circuits controlling feeding in broiler breeder chickens.
Dr Ian Dunn, University of Edinburgh 
£195,449

BB/L000288/1 
Investigating how the type and quantity of food affect foraging behaviour and the neural circuits controlling feeding in broiler breeder chickens.
Dr Richard D'Eath,  SRUC 
£313,937

BB/J017183/1 
Parameterisation of developmental networks to understand periodic patterning.
Dr Denis Headon, University of Edinburgh 
£330,680

BB/J015245/1 
The type III secretion system 'translocation-stop' activity of EspZ.
Professor Gad Frankel, Imperial College London 
£397,028

BB/J016721/1 
Genetic mapping of vector competence in Culicoides sonorensis.
Dr Mark Fife, The Pirbright Institute 
£660,938

BB/J017159/1 
Susceptibility of broiler chickens to Campylobacter: impacts of the gut environment and immune status on colonisation.
Professor Steven Rushton, Newcastle University 
£112,437

BB/K005642/1 
A novel bacterial defence system against antimicrobial peptides:
Implications for host colonisation in the foodborne pathogen Campylobacter jejuni.
Professor Mark Stevens, University of Edinburgh 
£105,169

BB/J016667/1 
Susceptibility of broiler chickens to Campylobacter: impacts of the gut environment and immune status on colonisation.
Professor Julian Ketley, University of Leicester 
£287,749

BB/L004046/1 
Understanding resistance and differential vaccine responses to
Eimeria in the chicken - novel biomarkers and genetic control.
Dr Damer Blake, Royal Veterinary College 
£340,604

BB/J018937/1 
Genetic basis of reproductive and plumage polymorphism in the ruff.
Professor Terence Burke, University of Sheffield 
£338,513

BB/J01513X/1 
Development of a vaccine to control poultry red mite.
Dr Alasdair Nisbet, Moredun Research
Institute
£402,644

BB/K007092/1 
Cute-Egg, improvement of eggshell cuticle quality to reduce vertical transmission of zoonotic and pathogenic organisms.
Dr Ian Dunn, University of Edinburgh 
£378,489

BB/L004003/1 
Understanding resistance and differential vaccine responses to
Eimeria in the chicken - novel biomarkers and genetic control.
Professor Peter Kaiser, University of Edinburgh 
£379,303

BB/K006096/1 
Cute-Egg, improvement of eggshell cuticle quality to reduce vertical transmission of zoonotic and pathogenic organisms.
Dr Maureen Bain, University of Glasgow 
£128,710

BB/K004484/1 
Epi-SEQ - Molecular epidemiology of epizootic diseases using next
generation sequencing technology.
Professor Daniel Haydon, University of Glasgow 
£272,856

BB/L004372/1 
13TSB_SynBio A synthetic biology-based approach to engineering triterpenoid saponins and optimisation for industrial
applications.
Professor Anne Osbourn, John Innes Centre 
£190,731

BB/L002353/1 
Cross-modality integration of sensory signals leading to initiation of locomotion.
Dr Stephen Soffe, University of Bristol 
£431,575

BB/L014262/1 
ANIHWA call 1: MADISUP. Marek's Disease Virus induced immunosuppression: From diagnosis to vaccination.
Professor Venugopal Nair, The Pirbright Institute 
£315,396

BB/L006081/1 
The social dynamics of cultural behaviour: transmission biases and adaptive social learning strategies in wild great tits.
Professor Ben Sheldon, University of Oxford 
£611,111

BB/L002264/1 
Cognitive decline during ageing: understanding the roles of
developmental and adult stress.
Dr Karen Spencer, University of St Andrews 
£491,909

BB/L00111X/1 
Cross-modality integration of sensory signals leading to
initiation of locomotion.
Dr Wenchang Li, University of St Andrews 
£349,602

BB/L000571/1 
Investigating how the type and quantity of food affect foraging
behaviour and the neural circuits controlling feeding in broiler
breeder chickens.
Dr Timothy Boswell, Newcastle University 
£24,731

BB/L000814/1 
Cross-modality integration of sensory signals leading to initiation of locomotion.
Professor Roman Borisyuk, University of Plymouth 
£271,482


Acknowledgment:

"Contains data obtained from the Biotechnology and Biological Sciences Research Council (BBSRC). The data is protected by copyright, database right and related rights, and all such rights are reserved by the BBSRC. Use of the data is subject to terms imposed by the BBSRC and available on the BBSRC website. The BBSRC has not endorsed or otherwise specifically approved this use of the BBSRC data".